Timing depends on your goal. For sleep support, many prefer evening or before bed, often with food if the stomach is sensitive. For daytime stress support, morning/early afternoon or split dosing may be used. Be careful when combining with high caffeine (stimulants) or sedative medicines, as effects may change. If you use regular medication or have chronic conditions, timing should be planned with a clinician. The best timing is the one you tolerate well and can follow consistently.