Safety has two parts: (1) product quality, (2) fit with your health profile. Quality depends on standardization (withanolide content), reputable manufacturing, testing reports, and transparent labeling. Fit depends on your conditions, medications, pregnancy/breastfeeding status, and prior side effects. Some users report stomach upset, drowsiness, or headaches; rarer serious issues have been reported. So it is not “safe for everyone.” A safer approach is cautious trial, starting low, monitoring effects, and stopping if concerns appear. The biggest risks are poor-quality products and uncontrolled use.