Editorial note
Map of Health content is prepared with an evidence-based approach. References are provided for transparency.
Medical disclaimer
This content is for informational purposes only and does not replace professional medical advice, diagnosis, or treatment. If you have an urgent medical concern, seek immediate care.
"Cosmetic ingredients used together can create a synergistic effect, leading to more effective results and balanced skin health."
On this page:
COSMETIC THAT SHOULD BE USED TOGETHER
| Combination | Effect | Usage | Who | Warning |
| Niacinamide + Zinc | Acne control, sebum balance | Morning and/or evening | Oily or acne-prone skin | Should not be used with acids |
| Niacinamide + Retinol | Retinol renews skin, niacinamide soothes | Evening | Mature and dry skin | Use with caution during pregnancy |
| Niacinamide + Azelaic Acid | Anti-inflammatory synergy for rosacea and acne | Morning and/or evening | Oily skin types | Avoid strong acids in same routine |
| Niacinamide + Arbutin | Suppresses melanin, brightens skin tone | Night | Sensitive and dry skin | Monitor irritation-prone skin |
| Peptide + Copper Peptide | Collagen increase, elasticity | Morning | Sensitive, bruised skin | Use in low concentrations around eyes |
| Caffeine + Green Tea Extract | Reduces under-eye puffiness and dark circles | Evening | Dry or mature skin | Should support barrier repair |
| AHA + PHA | Gentle exfoliation and skin renewal | Evening | Sensitive | Caution around eye area |
| Aloe Vera + Panthenol | Soothes irritation, sunburn, sensitivity | Day and night | Sensitive and dry skin | Start after allergy testing |
| Salicylic Acid + Lactic Acid | Pore cleansing, skin renewal | Evening | Oily and combination skin | Recommended for night use only |
| Salicylic Acid + Tea Tree Oil | Antibacterial, anti-inflammatory (acne) | Evening | Oily and acne-prone skin | Use with caution with niacinamide |
| Hyaluronic Acid + Glycerin | Deep hydration, retains water | Morning | Dry skin types | Should be supported with moisturizer |
| Vitamin C + Vitamin E + Ferulic Acid | Increases antioxidant power 4x, reduces UV damage | Morning | Oily skin types | May be drying in high doses |
| Retinol + Peptides | Renews skin, restores barrier | Evening | Dry or mature skin | Apply with SPF in morning |
| Retinol + Bakuchiol | Enhances retinol effect, reduces irritation | Evening | Spot-prone skin | Apply with SPF in morning |
| Retinol + Ceramide | Repairs barrier after renewal | Evening | Mature skin | Alternate use with retinol at night |
| Hyaluronic Acid + Vitamin C | Radiance and intense hydration | Morning | All skin types | Vitamin C must be stable |
Assoc. Prof. Muhammet Emin Çam
Rector Advisor, Vice Dean, and Faculty Member - Istanbul Kent University, Faculty of Pharmacy, Departmant of Pharmocology
Visiting Researcher&Lecturer - University College London, Mechanical Engineering and Faculty of Medicine, UK
Visiting Lecturer - University of Aveiro, Faculty of Biomedical Engineering, Portugal
Visiting Researcher&Lecturer - University College London, Mechanical Engineering and Faculty of Medicine, UK
Visiting Lecturer - University of Aveiro, Faculty of Biomedical Engineering, Portugal