Published: 2026-01-28
Updated: 2026-01-28
Editorial note
Map of Health content is prepared with an evidence-based approach. References are provided for transparency.
Medical disclaimer
This content is for informational purposes only and does not replace professional medical advice, diagnosis, or treatment. If you have an urgent medical concern, seek immediate care.
"A massive study of 125,000 women in the UK has proven that menopause causes physical changes in the brain similar to those seen in Alzheimer's disease."
On this page:
Key Critical Findings
- Cellular Loss: During menopause, significant gray matter loss is observed in brain regions involved in memory (hippocampus), learning, and emotion management.
- HRT Is Not a Solution: Hormone Replacement Therapy (HRT) has been found not to prevent these physical losses and does not always have a positive impact on mental health.
- Risk in Women: The fact that women account for approximately two-thirds of Alzheimer's cases can be explained by the brain becoming more vulnerable during menopause.
How to Reduce Risk?
Scientists recommend the following lifestyle changes from an early age to prevent physical changes:
1. Regular physical exercise.
2. Avoiding smoking and alcohol.
3. Seeking professional support to protect mental health.
In summary: Menopause is not just a hormonal change, but a process that directly affects brain structure. Taking the mental and physical changes during this period seriously is critical for managing the risk of future dementia.
