What does “post-antibiotic” mean?
In everyday use, “post-antibiotic” can mean different things—and the distinction matters. Clinically, it often refers to the period after an antibiotic course, when the gut microbiota may be recovering (post-antibiotic recovery). In pharmacology, “post-antibiotic effect” describes the phenomenon where bacterial growth remains suppressed even after antibiotic levels fall. In the supplement space, the term is sometimes mistakenly used in place of “postbiotic.” If the goal is supporting the gut after antibiotics, strategies may include fiber-rich (prebiotic) foods, fermented foods, and—when appropriate—evidence-based probiotic or postbiotic options. Not everyone needs the same intervention: those with antibiotic-associated diarrhea, prolonged broad-spectrum exposure, prior C. difficile history, or complex medication profiles benefit from a more tailored, cautious approach anchored to symptoms, risk factors, and product-specific evidence.