Zinc and magnesium deficiencies may both start with non-specific fatigue, but typical clues differ. Zinc deficiency can be associated with frequent infections, delayed wound healing, reduced taste/smell, appetite changes, dry or irritated skin, and increased hair shedding. Magnesium deficiency more often affects neuromuscular function: cramps, twitching, tingling, restlessness, headaches/migraine tendency, fatigue, and—in severe cases—rhythm disturbances. Two practical caveats: (1) serum magnesium may not perfectly reflect intracellular status; risk factors and symptoms matter. (2) prolonged high-dose zinc can impair copper absorption, potentially leading to anemia and neurologic issues. Therefore, confirm need, choose an appropriate dose/duration, and monitor rather than combining supplements blindly.\n\nSource note: NIH ODS fact sheets on zinc and magnesium (deficiency symptoms, interactions, safety).