Yes, mouse feces can harm humans. One of the main risks occurs when droppings dry, become dust, and are inhaled during cleaning. This may create risk for infections such as hantavirus. Mouse feces can also contaminate food and surfaces, increasing the chance of bacterial infections. Areas with mouse feces should not be touched with bare hands, dry-swept, or vacuumed. The area should first be ventilated, then moistened with disinfectant and cleaned carefully. Using gloves, a mask, and proper hygiene practices is important for preventing hantavirus and other rodent-borne diseases.